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Folate-PEG-NHS聚乙二醇衍生物的制備方法介紹-葉酸聚乙二醇

西安瑞禧生物科技有限公司是國(guó)內(nèi)最大的PEG生產(chǎn)制造商，我們提供末端活性基團(tuán)取代率97%+以上的產(chǎn)品，產(chǎn)品穩(wěn)定 保存2年以上。

2019年瑞禧生物的基礎(chǔ)PEG產(chǎn)品大幅降價(jià)，降價(jià)產(chǎn)品包括有NH2-PEG-Biotin，DBCO-PEG-NH2，MAL-PEG-COOH，HS-PEG-COOH，SCM-PEG-MAL，Alkyne -PEG-COOH等等不同產(chǎn)品。

Sc-PEG 專利分析：

NH2-PEG-COOH

NH2-PEG-MAL

NH2-PEG-N3

NH2-PEG-Alkyne

NH2-PEG-SH

NH2-PEG-Biotin

NH2-PEG-OPSS

NH2-PEG-OH

NH2-PEG-Hydrazide

NH2-PEG-Silane

NH2-peg-Acrylates

NH2-peg-Lipoicacid

NH2-peg-Acetylthio

NH2-PEG-NitrophenylCarbonates (NPC)

NH2-PEG-ValericAcids

NH2-PEG-Acrylamide

NH2-PEG-Bromide(Br)

NH2-PEG-Vinylsulfone(VS)

NH2-PEG-Methacrylate(MA)

NH2-PEG-Iodoacetate(IA)

NH2-PEG-Chloride

DBCO-PEG-NH2

TCO-PEG-NH2

Tetrazine-PEG-NH2

NH2-PEG-Folate

NH2-PEG-CHEMS

Roche公司的長(zhǎng)效干擾素產(chǎn)品專利分析：

MAL-PEG-COOH

NHS-PEG-COOH

N3-PEG-COOH

Alkyne-PEG-COOH

HS-PEG-COOH

Biotin-PEG-COOH

CHO-PEG-COOH

OPSS-PEG-COOH

Silane-peg-COOH

Acrylates-peg-COOH

Lipoicacid-peg-COOH

Tosylate-peg-COOH

NPC-PEG-COOH

SAS-PEG-COOH

SC-PEG-COOH

SCM-PEG-COOH

SG-PEG-COOH

SS-PEG-COOH

SVA-PEG-COOH

Epoxides-PEG-COOH

ValericAcids-PEG-COOH

Acrylamide-PEG-COOH

Bromide-PEG-COOH

VS-PEG-COOH

Methacrylate-PEG-COOH

IA-PEG-COOH

Chloride-PEG-COOH

DBCO-PEG-COOH

TCO-PEG-COOH

Tetrazine-PEG-COOH

Folate-PEG-COOH

CHEMS-PEG-COOH

西安瑞禧生物新的修飾策略：

采用新方法制備新的修飾劑

NHS-PEG-MAL

N3-PEG-MAL

Alkyne-PEG-MAL

Biotin-PEG-MAL

CHO-PEG-MAL

OPSS-PEG-MAL

Hydrazide-PEG-MAL

Silane-peg-MAL

Acrylates-peg-MAL

Lipoicacid-peg-MAL

Tosylate-peg-MAL

Aminooxy-PEG-MAL

NPC-PEG-MAL

SAS-PEG-MAL

SC-PEG-MAL

SCM-PEG-MAL

SG-PEG-MAL

SS-PEG-MAL

SVA-PEG-MAL

Epoxides-PEG-MAL

ValericAcids-PEG-MAL

Acrylamide-PEG-MAL

Bromide-PEG-MAL

VS-PEG-MAL

Methacrylate-PEG-MAL

IA-PEG-MAL

Chloride-PEG-MAL

DBCO-PEG-MAL

TCO-PEG-MAL

Tetrazine-PEG-MAL

Folate-PEG-MAL

CHEMS-PEG-MAL

西安瑞禧生物科技有限公司的方法：

N3-PEG-NHS

Alkyne-PEG-NHS

HS-PEG-NHS

Biotin-PEG-NHS

CHO-PEG-NHS

OPSS-PEG-NHS

Hydrazide-PEG-NHS

Silane-peg-NHS

Acrylates-peg-NHS

Lipoicacid-peg-NHS

Tosylate-peg-NHS

Acetylthio-peg-NHS

NPC-PEG-NHS

Epoxides-PEG-NHS

ValericAcids-PEG-NHS

Bromide-PEG-NHS

VS-PEG-NHS

Methacrylate-PEG-NHS

IA-PEG-NHS

Chloride-PEG-NHS

DBCO-PEG-NHS

TCO-PEG-NHS

Tetrazine-PEG-NHS

Folate-PEG-NHS

CHEMS-PEG-NHS

PEG修飾劑的批量制備取得了成功：

Biotin-PEG-SH

CHO-PEG-SH

Hydrazide-PEG-SH

Silane-peg-SH

Acrylates-peg-SH

Lipoicacid-peg-SH

Tosylate-peg-SH

Aminooxy-PEG-SH

NPC-PEG-SH

SAS-PEG-SH

SC-PEG-SH

SCM-PEG-SH

SG-PEG-SH

SS-PEG-SH

SVA-PEG-SH

Epoxides-PEG-SH

ValericAcids-PEG-SH

Acrylamide-PEG-SH

Bromide-PEG-SH

Methacrylate-PEG-SH

IA-PEG-SH

Chloride-PEG-SH

DBCO-PEG-SH

TCO-PEG-SH

Tetrazine-PEG-SH

Folate-PEG-SH

CHEMS-PEG-SH