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Home > Products > Block Copolymers> PLGA-PEG> PLGA5000-PEG2000-PLGA5000
PLGA5000-PEG2000-PLGA5000
Catalog # Pkg Size Price Quantity Shopping Cart
R-PL1002-12KD 1g ¥ 1150
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R-PL1002-12KD 5g ¥ 3735
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R-PL1002-12KD 10g ¥ 5750
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結(jié)構(gòu)式
外觀 白色/類白色固體 (外觀取決于分子量)
分子量 12000
溶解度 三氯甲烷/二氯甲烷
CAS號(hào) N/A
質(zhì)量控制 取代率>90% PDI<1.4
儲(chǔ)存條件 -20℃
保存時(shí)間 1年
其他信息 PLGA可選:LA/GA=50/50 LA/GA=25/75

Amphiphilic block copolymers comprised of poly(lactic acid-co-glycolic acid) and poly(ethylene glycol) are thermogelling materials with biodegradable blocks. The thermogel forming biodegradable delivery system has two major benefit : 1) First, thermogelation allows for delivery over the course of a period of time after introduction of what is initially a liquid; 2) The material safely biodegrades away once it is no longer necessary to lactic and glycolic acids as well as the water-soluble poly(ethylene glycol) block, which at molecular weights below 20KDa are safely eliminated from the body by the kidneys.

The thermogelation properties of poly(lactic acid-co-glycolic acid)-block-poly(ethylene glycol)-block-poly(lactic acid-co-glycolic acid) (PLGA-PEG-PLGA) copolymers have been extensively used in research for controlled delivery.

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