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DBCO-PEG4-Desthiobiotin
| Catalog # | Pkg Size | Price | Quantity | Shopping Cart |
|---|---|---|---|---|
| R-CD-030 | 10mg | ￥ 2384 | 加入購(gòu)物車 | |
| R-CD-030 | 25mg | ￥ 4464 | 加入購(gòu)物車 | |
Datasheet
MSDS
COA
結(jié)構(gòu)式
| 外觀 | Colorless to slightly yellow oil |
| 分子量 | 719.87 |
| 溶解度 | DMSO, DMF, DCM, THF, Chloroform |
| CAS號(hào) | N/A |
| 質(zhì)量控制 | 95% |
| 儲(chǔ)存條件 | -20℃ |
| 保存時(shí)間 | 1 year |
| 其他信息 | N/A |
Desthiobiotin is a single-ring, sulfur-free analog of biotin that binds to streptavidin with nearly equal specificity but less affinity than biotin (Kd = 1011 vs. 1015M, respectively). Consequently, desthiobiotinylated proteins can be eluted readily and specifically from streptavidin affinity resin using mild conditions based on competitive displacement with free biotin. For pull-down experiments with biological samples, this soft-release characteristic of desthiobiotin also helps to minimize co-purification of endogenous biotinylated molecules, which remain bound to streptavidin upon elution of the target protein complexes with free biotin.
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